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TLR2 mediates renal apoptosis in neonatal mice subjected experimentally to obstructive nephropathy

Urinary tract obstruction during renal development leads to inflammation, tubular apoptosis, and interstitial fibrosis. Toll like receptors (TLRs) expressed on leukocytes, myofibroblasts and renal cells play a central role in acute inflammation. TLR2 is activated by endogenous danger signals in the...

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Detalles Bibliográficos
Autores principales: Wyczanska, Maja, Rohling, Jana, Keller, Ursula, Benz, Marcus R., Kirschning, Carsten, Lange-Sperandio, Bärbel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684073/
https://www.ncbi.nlm.nih.gov/pubmed/38015955
http://dx.doi.org/10.1371/journal.pone.0294142