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TLR2 mediates renal apoptosis in neonatal mice subjected experimentally to obstructive nephropathy
Urinary tract obstruction during renal development leads to inflammation, tubular apoptosis, and interstitial fibrosis. Toll like receptors (TLRs) expressed on leukocytes, myofibroblasts and renal cells play a central role in acute inflammation. TLR2 is activated by endogenous danger signals in the...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684073/ https://www.ncbi.nlm.nih.gov/pubmed/38015955 http://dx.doi.org/10.1371/journal.pone.0294142 |