Nonsense mutation suppression is enhanced by targeting different stages of the protein synthesis process

The introduction of premature termination codons (PTCs), as a result of splicing defects, insertions, deletions, or point mutations (also termed nonsense mutations), lead to numerous genetic diseases, ranging from rare neuro-metabolic disorders to relatively common inheritable cancer syndromes and m...

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Detalles Bibliográficos
Autores principales: Wittenstein, Amnon, Caspi, Michal, Rippin, Ido, Elroy-Stein, Orna, Eldar-Finkelman, Hagit, Thoms, Sven, Rosin-Arbesfeld, Rina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684085/
https://www.ncbi.nlm.nih.gov/pubmed/37943958
http://dx.doi.org/10.1371/journal.pbio.3002355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684085/
https://www.ncbi.nlm.nih.gov/pubmed/37943958
http://dx.doi.org/10.1371/journal.pbio.3002355

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