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A Comparison of Treatment Effect Sizes in Matched Phase 2 and Phase 3 Trials of Advanced Therapeutics in Inflammatory Bowel Disease: Systematic Review and Meta-Analysis

INTRODUCTION: Phase 2 trials are fundamental to the rational and efficient design of phase 3 trials. We aimed to determine the relationship of treatment effect size estimates from phase 2 and phase 3 clinical trials on advanced therapeutics in inflammatory bowel disease. METHODS: MEDLINE, EMBASE, CE...

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Detalles Bibliográficos
Autores principales: Hanzel, Jurij, Solitano, Virginia, Zou, Lily, Zou, G.Y., Peyrin-Biroulet, Laurent, Danese, Silvio, Singh, Siddharth, Ma, Christopher, Wils, Pauline, Jairath, Vipul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684248/
https://www.ncbi.nlm.nih.gov/pubmed/37578211
http://dx.doi.org/10.14309/ctg.0000000000000629