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Evolution of Ritlecitinib Population Pharmacokinetic Models During Clinical Drug Development

BACKGROUND: Ritlecitinib is an oral Janus kinase 3/tyrosine kinase expressed in hepatocellular carcinoma family inhibitor undergoing parallel clinical development for alopecia areata, vitiligo, ulcerative colitis, Crohn’s disease, and rheumatoid arthritis. OBJECTIVE: As studies read out simultaneous...

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Detalles Bibliográficos
Autores principales: Wojciechowski, Jessica, S Purohit, Vivek, Huh, Yeamin, Banfield, Christopher, Nicholas, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684409/
https://www.ncbi.nlm.nih.gov/pubmed/37917289
http://dx.doi.org/10.1007/s40262-023-01318-3