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Osteopontin enhances the effect of treadmill training and promotes functional recovery after spinal cord injury

In this study, we examined the combined impact of osteopontin (OPN) and treadmill training on mice with spinal cord injury (SCI). OPN was overexpressed by injecting AAV9-SPP1-GFP into the sensorimotor cortex, followed by a left incomplete C5 crush injury two weeks later. Mice (Ex or Ex + OPN group)...

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Detalles Bibliográficos
Autores principales: Wang, Yunhang, Su, Hong, Zhong, Juan, Zhan, Zuxiong, Zhao, Qin, Liu, Yuan, Li, Sen, Wang, Haiyan, Yang, Ce, Yu, Lehua, Tan, Botao, Yin, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684450/
https://www.ncbi.nlm.nih.gov/pubmed/38015348
http://dx.doi.org/10.1186/s43556-023-00154-y