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Oncolytic adenoviruses expressing checkpoint inhibitors for cancer therapy

Despite the remarkable success of immune checkpoint inhibitors (ICIs), primary resistance to ICIs causes only subsets of patients to achieve durable responses due to the complex tumor microenvironment (TME). Oncolytic viruses (OVs) can overcome the immunosuppressive TME and promote systemic antitumo...

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Detalles Bibliográficos
Autores principales: Xie, Daoyuan, Tian, Yaomei, Hu, Die, Wang, Yuanda, Yang, Yuling, Zhou, Bailing, Zhang, Rui, Ren, Zhixiang, Liu, Mohan, Xu, Jie, Dong, Chunyan, Zhao, Binyan, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684539/
https://www.ncbi.nlm.nih.gov/pubmed/38016957
http://dx.doi.org/10.1038/s41392-023-01683-2