Label-free identification of protein aggregates using deep learning

Protein misfolding and aggregation play central roles in the pathogenesis of various neurodegenerative diseases (NDDs), including Huntington’s disease, which is caused by a genetic mutation in exon 1 of the Huntingtin protein (Httex1). The fluorescent labels commonly used to visualize and monitor th...

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Detalles Bibliográficos
Autores principales: Ibrahim, Khalid A., Grußmayer, Kristin S., Riguet, Nathan, Feletti, Lely, Lashuel, Hilal A., Radenovic, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684545/
https://www.ncbi.nlm.nih.gov/pubmed/38016971
http://dx.doi.org/10.1038/s41467-023-43440-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684545/
https://www.ncbi.nlm.nih.gov/pubmed/38016971
http://dx.doi.org/10.1038/s41467-023-43440-7

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