Functional brain region-specific neural spheroids for modeling neurological diseases and therapeutics screening

3D spheroids have emerged as powerful drug discovery tools given their high-throughput screening (HTS) compatibility. Here, we describe a method for generating functional neural spheroids by cell-aggregation of differentiated human induced pluripotent stem cell (hiPSC)-derived neurons and astrocytes...

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Detalles Bibliográficos
Autores principales: Strong, Caroline E., Zhang, Jiajing, Carrasco, Martin, Kundu, Srikanya, Boutin, Molly, Vishwasrao, Harshad D., Liu, Jiamin, Medina, Angelica, Chen, Yu-Chi, Wilson, Kelli, Lee, Emily M., Ferrer, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684574/
https://www.ncbi.nlm.nih.gov/pubmed/38017066
http://dx.doi.org/10.1038/s42003-023-05582-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684574/
https://www.ncbi.nlm.nih.gov/pubmed/38017066
http://dx.doi.org/10.1038/s42003-023-05582-8

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