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Deficiency of N-linked glycosylation impairs immune function of B7-H6

B7-H6 is a novel immune checkpoint molecule that triggers NK cell cytotoxicity, but the role of N-glycosylation in B7-H6 is poorly understood. We here identified the existence of N-glycosylation of B7-H6 in different cell lines and exogenous expression cells by PNGase F digestion and tunicamycin blo...

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Detalles Bibliográficos
Autores principales: Chen, Hanqing, Zhang, Yang, Shen, Yu, Jiang, Liang, Zhang, Guangbo, Zhang, Xueguang, Xu, Yang, Fu, Fengqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684670/
https://www.ncbi.nlm.nih.gov/pubmed/38035117
http://dx.doi.org/10.3389/fimmu.2023.1255667