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APOE4 allele-specific associations between diet, multimodal biomarkers, and cognition among Puerto Rican adults in Massachusetts

BACKGROUND: Apolipoprotein E (APOE) is the strongest genetic risk factor for sporadic Alzheimer’s Disease (AD), and the ε4 allele (APOE4) may interact with lifestyle factors that relate to brain structural changes, underlying the increased risk of AD. However, the exact role of APOE4 in mediating in...

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Detalles Bibliográficos
Autores principales: Guan, Yi, Cheng, Chia Hsin, Bellomo, Luis I., Narain, Sriman, Bigornia, Sherman J., Garelnabi, Mahdi O., Scott, Tammy, Ordovás, José M., Tucker, Katherine L., Bhadelia, Rafeeque, Koo, Bang-Bon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684694/
https://www.ncbi.nlm.nih.gov/pubmed/38035273
http://dx.doi.org/10.3389/fnagi.2023.1285333