High population frequencies of MICA copy number variations originate from independent recombination events

MICA is a stress-induced ligand of the NKG2D receptor that stimulates NK and T cell responses and was identified as a key determinant of anti-tumor immunity. The MICA gene is located inside the MHC complex and is in strong linkage disequilibrium with HLA-B. While an HLA-B*48-linked MICA deletion-hap...

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Detalles Bibliográficos
Autores principales: Klussmeier, Anja, Putke, Kathrin, Klasberg, Steffen, Kohler, Maja, Sauter, Jürgen, Schefzyk, Daniel, Schöfl, Gerhard, Massalski, Carolin, Schäfer, Gesine, Schmidt, Alexander H., Roers, Axel, Lange, Vinzenz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684724/
https://www.ncbi.nlm.nih.gov/pubmed/38035108
http://dx.doi.org/10.3389/fimmu.2023.1297589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684724/
https://www.ncbi.nlm.nih.gov/pubmed/38035108
http://dx.doi.org/10.3389/fimmu.2023.1297589

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