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Antigen density quantification of cell-surface immunotherapy targets by flow cytometry: Multi-antigen assay of neuroblastoma bone marrow metastasis

The central role of target antigen density on chimeric antigen receptor T cell potency highlights the need for accurate measurement of antigen levels on clinical tumor samples. Here, we present a protocol for quantifying antigen density for six cell-surface antigens on neuroblastoma cells metastatic...

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Detalles Bibliográficos
Autores principales: Radosevich, Molly T., Bornheimer, Scott J., Mehrpouryan, Majid, Sahaf, Bita, Oak, Jean S., Mackall, Crystal L., Heitzeneder, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684814/
https://www.ncbi.nlm.nih.gov/pubmed/37967014
http://dx.doi.org/10.1016/j.xpro.2023.102709