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Antigen density quantification of cell-surface immunotherapy targets by flow cytometry: Multi-antigen assay of neuroblastoma bone marrow metastasis
The central role of target antigen density on chimeric antigen receptor T cell potency highlights the need for accurate measurement of antigen levels on clinical tumor samples. Here, we present a protocol for quantifying antigen density for six cell-surface antigens on neuroblastoma cells metastatic...
Autores principales: | Radosevich, Molly T., Bornheimer, Scott J., Mehrpouryan, Majid, Sahaf, Bita, Oak, Jean S., Mackall, Crystal L., Heitzeneder, Sabine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684814/ https://www.ncbi.nlm.nih.gov/pubmed/37967014 http://dx.doi.org/10.1016/j.xpro.2023.102709 |
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