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Characterization of the TCRβ repertoire of peripheral MR1-restricted MAIT cells in psoriasis vulgaris patients

Psoriasis vulgaris (PV) is an inflammatory skin disease largely driven by aberrant αβT cells. Mucosal-associated invariant T (MAIT) cells, which constitute the largest circulating innate-like αβT cell community in human adults, are characterized by a semi-invariant TCRVα7.2 receptor and MR1-restrict...

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Detalles Bibliográficos
Autores principales: Jirouš Drulak, Maja, Grgić, Zvonimir, Plužarić, Vera, Šola, Marija, Opačak-Bernardi, Teuta, Viljetić, Barbara, Glavaš, Kristina, Tolušić-Levak, Maja, Periša, Vlatka, Mihalj, Martina, Štefanić, Mario, Tokić, Stana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684872/
https://www.ncbi.nlm.nih.gov/pubmed/38017021
http://dx.doi.org/10.1038/s41598-023-48321-z