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The treatment with trandolapril and losartan attenuates pressure and volume overload alternations of cardiac connexin-43 and extracellular matrix in Ren-2 transgenic rats

Heart failure (HF) is life-threatening disease due to electro-mechanical dysfunction associated with hemodynamic overload, while alterations of extracellular matrix (ECM) along with perturbed connexin-43 (Cx43) might be key factors involved. We aimed to explore a dual impact of pressure, and volume...

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Detalles Bibliográficos
Autores principales: Sykora, Matus, Kratky, Vojtech, Cervenka, Ludek, Kopkan, Libor, Tribulova, Narcis, Szeiffova Bacova, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684879/
https://www.ncbi.nlm.nih.gov/pubmed/38017033
http://dx.doi.org/10.1038/s41598-023-48259-2