Nuclear actin polymerization rapidly mediates replication fork remodeling upon stress by limiting PrimPol activity

Cells rapidly respond to replication stress actively slowing fork progression and inducing fork reversal. How replication fork plasticity is achieved in the context of nuclear organization is currently unknown. Using nuclear actin probes in living and fixed cells, we visualized nuclear actin filamen...

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Detalles Bibliográficos
Autores principales: Palumbieri, Maria Dilia, Merigliano, Chiara, González-Acosta, Daniel, Kuster, Danina, Krietsch, Jana, Stoy, Henriette, von Känel, Thomas, Ulferts, Svenja, Welter, Bettina, Frey, Joël, Doerdelmann, Cyril, Sanchi, Andrea, Grosse, Robert, Chiolo, Irene, Lopes, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684888/
https://www.ncbi.nlm.nih.gov/pubmed/38016948
http://dx.doi.org/10.1038/s41467-023-43183-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684888/
https://www.ncbi.nlm.nih.gov/pubmed/38016948
http://dx.doi.org/10.1038/s41467-023-43183-5

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