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The consequences of cohesin mutations in myeloid malignancies

Recurrent somatic mutations in the genes encoding the chromatin-regulatory cohesin complex and its modulators occur in a wide range of human malignancies including a high frequency in myeloid neoplasms. The cohesin complex has a ring-like structure which can enclose two strands of DNA. A first funct...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Shubhra Ashish, Dias, Eve, Nieto-Aliseda, Andrea, Buschbeck, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684907/
https://www.ncbi.nlm.nih.gov/pubmed/38033389
http://dx.doi.org/10.3389/fmolb.2023.1319804