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Targeting acidic pre-metastatic niche in lungs by pH low insertion peptide and its utility for anti-metastatic therapy

Dysregulated extracellular pH, the universal feature of tumor, works as an evolutional force to drive dissemination of tumor cells. It is well-established that tumor acidity is associated with tumor growth and metastasis. However, the pH of pre-metastatic niche remains unclear. We hypothesized that...

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Detalles Bibliográficos
Autores principales: Matsui, Toma, Toda, Yuki, Sato, Haruka, Itagaki, Rina, Konishi, Kazuya, Moshnikova, Anna, Andreev, Oleg A., Hosogi, Shigekuni, Reshetnyak, Yana K., Ashihara, Eishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684925/
https://www.ncbi.nlm.nih.gov/pubmed/38033489
http://dx.doi.org/10.3389/fonc.2023.1258442