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How to engineer aerosol particle properties and biopharmaceutical performance of propellant inhalers

Given the environmental compulsion to reformulate pressurised metered dose inhalers (pMDI) using new propellants with lower global warming potential, this study investigated how non-volatile excipients can be used to engineer aerosol particle microphysics and drug release. The dynamics of change in...

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Detalles Bibliográficos
Autores principales: Akhuemokhan, Precious, Green, Natalie Armstrong, Haddrell, Allen, Lewis, David, Reid, Jonathan P., Forbes, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685293/
https://www.ncbi.nlm.nih.gov/pubmed/36738807
http://dx.doi.org/10.1016/j.ijpharm.2023.122676