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Progesterone receptor membrane component 1 facilitates Ca(2+) signal amplification between endosomes and the endoplasmic reticulum

Membrane contact sites (MCSs) between endosomes and the endoplasmic reticulum (ER) are thought to act as specialized trigger zones for Ca(2+) signaling, where local Ca(2+) released via endolysosomal ion channels is amplified by ER Ca(2+)-sensitive Ca(2+) channels into global Ca(2+) signals. Such amp...

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Detalles Bibliográficos
Autores principales: Gunaratne, Gihan S., Kumar, Sushil, Lin-Moshier, Yaping, Slama, James T., Brailoiu, Eugen, Patel, Sandip, Walseth, Timothy F., Marchant, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685313/
https://www.ncbi.nlm.nih.gov/pubmed/37866635
http://dx.doi.org/10.1016/j.jbc.2023.105378