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Regioselective ortho halogenation of N-aryl amides and ureas via oxidative halodeboronation: harnessing boron reactivity for efficient C–halogen bond installation

The installation of the C–halogen bond at the ortho position of N-aryl amides and ureas represents a tool to prepare motifs that are ubiquitous in biologically active compounds. To construct such prevalent bonds, most methods require the use of precious metals and a multistep process. Here we report...

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Detalles Bibliográficos
Autores principales: Shinde, Ganesh H., Ghotekar, Ganesh S., Amombo Noa, Francoise M., Öhrström, Lars, Norrby, Per-Ola, Sundén, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685333/
https://www.ncbi.nlm.nih.gov/pubmed/38033885
http://dx.doi.org/10.1039/d3sc04628a