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A highly diastereoselective strain-release Doyle–Kirmse reaction: access to functionalized difluoro(methylene)cyclopropanes

Difluoro(methylene)cyclopropanes (F2MCPs) show better anti-cancer properties and chemical reactivities compared to their nonfluorinated analogues. However, catalytic stereoselective methods to access these privileged motifs still remain a challenging goal. The Doyle–Kirmse reaction is a powerful str...

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Detalles Bibliográficos
Autores principales: Midya, Suparnak, Hari, Durga Prasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685340/
https://www.ncbi.nlm.nih.gov/pubmed/38033902
http://dx.doi.org/10.1039/d3sc04749k