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Cobalt-Catalyzed Efficient Asymmetric Hydrogenation of α-Primary Amino Ketones

[Image: see text] Based on an amino-group-assisted coordination strategy and a proton-shuttle-activated outer-sphere mode, the cobalt-catalyzed asymmetric hydrogenation of α-primary amino ketones has been developed, resulting in the efficient synthesis of chiral vicinal amino alcohols bearing functi...

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Detalles Bibliográficos
Autores principales: Yang, Huiwen, Hu, Yanhua, Zou, Yashi, Zhang, Zhenfeng, Zhang, Wanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685343/
https://www.ncbi.nlm.nih.gov/pubmed/38034968
http://dx.doi.org/10.1021/jacsau.3c00524