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Inhibition of SIRT6 aggravates p53-mediated ferroptosis in acute lung injury in mice

Although studies have shown that protein 53 (p53)-mediated ferroptosis is involved in acute lung injury (ALI), the mechanism of its regulation remains unclear. The protective effects of Sirtuin 6 (SIRT6), a histone deacetylase, have been demonstrated in multiple diseases; however, further studies ar...

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Detalles Bibliográficos
Autores principales: Cao, Yuanyuan, Peng, Tian, Ai, Chenmu, Li, Zhiwang, Lei, Xiaobao, Li, Guicheng, Li, Tao, Wang, Xiang, Cai, Shumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685376/
https://www.ncbi.nlm.nih.gov/pubmed/38034611
http://dx.doi.org/10.1016/j.heliyon.2023.e22272