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Deep Learning Dynamic Allostery of G-Protein-Coupled Receptors
[Image: see text] G-protein-coupled receptors (GPCRs) make up the largest superfamily of human membrane proteins and represent primary targets of ∼1/3 of currently marketed drugs. Allosteric modulators have emerged as more selective drug candidates compared with orthosteric agonists and antagonists....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685416/ https://www.ncbi.nlm.nih.gov/pubmed/38034960 http://dx.doi.org/10.1021/jacsau.3c00503 |