Antibody-Based Imaging of Bioreductive Prodrug Release in Hypoxia

[Image: see text] Regions of hypoxia occur in most tumors and are a predictor of poor patient prognosis. Hypoxia-activated prodrugs (HAPs) provide an ideal strategy to target the aggressive, hypoxic, fraction of a tumor, while protecting the normal tissue from toxicity. A key challenge associated wi...

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Detalles Bibliográficos
Autores principales: Tosun, Çağla, Wallabregue, Antoine L. D., Mallerman, Maxim, Phillips, Sarah E., Edwards, Claire M., Conway, Stuart J., Hammond, Ester M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685431/
https://www.ncbi.nlm.nih.gov/pubmed/38034969
http://dx.doi.org/10.1021/jacsau.3c00562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685431/
https://www.ncbi.nlm.nih.gov/pubmed/38034969
http://dx.doi.org/10.1021/jacsau.3c00562

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