Combined Computational–Biochemical Approach Offers an Accelerated Path to Membrane Protein Solubilization

[Image: see text] Membrane proteins are difficult to isolate and purify due to their dependence on the surrounding lipid membrane for structural stability. Detergents are often used to solubilize these proteins, with this approach requiring a careful balance between protein solubilization and denatu...

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Detalles Bibliográficos
Autores principales: Pierce, Mariah R., Ji, Jingjing, Novak, Sadie X., Sieburg, Michelle A., Nangia, Shivangi, Nangia, Shikha, Hougland, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685452/
https://www.ncbi.nlm.nih.gov/pubmed/37939203
http://dx.doi.org/10.1021/acs.jcim.3c00917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685452/
https://www.ncbi.nlm.nih.gov/pubmed/37939203
http://dx.doi.org/10.1021/acs.jcim.3c00917

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