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Combined Computational–Biochemical Approach Offers an Accelerated Path to Membrane Protein Solubilization
[Image: see text] Membrane proteins are difficult to isolate and purify due to their dependence on the surrounding lipid membrane for structural stability. Detergents are often used to solubilize these proteins, with this approach requiring a careful balance between protein solubilization and denatu...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685452/ https://www.ncbi.nlm.nih.gov/pubmed/37939203 http://dx.doi.org/10.1021/acs.jcim.3c00917 |