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miR-590-5p/Tiam1-mediated glucose metabolism promotes malignant evolution of pancreatic cancer by regulating SLC2A3 stability

BACKGROUND: T lymphoma invasion and metastasis 1 (Tiam1) is a tumor related gene that specifically activates Rho-like GTPases Rac1 and plays a critical role in the progression of various malignancies. Glycolysis plays an important role in cancer progression, it is crucial for supplying energy and pr...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Jin, Aihua, Quan, Xianglan, Shen, Xionghu, Zhou, Houkun, Zhao, Xingyu, Lin, Zhenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685474/
https://www.ncbi.nlm.nih.gov/pubmed/38017477
http://dx.doi.org/10.1186/s12935-023-03159-3