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miR-590-5p/Tiam1-mediated glucose metabolism promotes malignant evolution of pancreatic cancer by regulating SLC2A3 stability
BACKGROUND: T lymphoma invasion and metastasis 1 (Tiam1) is a tumor related gene that specifically activates Rho-like GTPases Rac1 and plays a critical role in the progression of various malignancies. Glycolysis plays an important role in cancer progression, it is crucial for supplying energy and pr...
Autores principales: | Liu, Ying, Jin, Aihua, Quan, Xianglan, Shen, Xionghu, Zhou, Houkun, Zhao, Xingyu, Lin, Zhenhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685474/ https://www.ncbi.nlm.nih.gov/pubmed/38017477 http://dx.doi.org/10.1186/s12935-023-03159-3 |
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