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Evaluation of causal associations between interleukin-18 levels and immune-mediated inflammatory diseases: a Mendelian randomization study

BACKGROUND: Altered interleukin (IL)-18 levels are associated with immune-mediated inflammatory diseases (IMIDs), but no studies have investigated their causal relationship. This study aimed to examine the causal associations between IL-18 and IMIDs. METHODS: We performed a two-sample Mendelian rand...

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Detalles Bibliográficos
Autores principales: Wu, Jialing, Zhang, Xi, Wu, Dongze, Jin, Ou, Gu, Jieruo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685486/
https://www.ncbi.nlm.nih.gov/pubmed/38031150
http://dx.doi.org/10.1186/s12920-023-01744-z