Sulfate limitation increases specific plasmid DNA yield and productivity in E. coli fed-batch processes

Plasmid DNA (pDNA) is a key biotechnological product whose importance became apparent in the last years due to its role as a raw material in the messenger ribonucleic acid (mRNA) vaccine manufacturing process. In pharmaceutical production processes, cells need to grow in the defined medium in order...

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Detalles Bibliográficos
Autores principales: Gotsmy, Mathias, Strobl, Florian, Weiß, Florian, Gruber, Petra, Kraus, Barbara, Mairhofer, Juergen, Zanghellini, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685491/
https://www.ncbi.nlm.nih.gov/pubmed/38017439
http://dx.doi.org/10.1186/s12934-023-02248-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685491/
https://www.ncbi.nlm.nih.gov/pubmed/38017439
http://dx.doi.org/10.1186/s12934-023-02248-2

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