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Sulfate limitation increases specific plasmid DNA yield and productivity in E. coli fed-batch processes

Plasmid DNA (pDNA) is a key biotechnological product whose importance became apparent in the last years due to its role as a raw material in the messenger ribonucleic acid (mRNA) vaccine manufacturing process. In pharmaceutical production processes, cells need to grow in the defined medium in order...

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Detalles Bibliográficos
Autores principales:	Gotsmy, Mathias, Strobl, Florian, Weiß, Florian, Gruber, Petra, Kraus, Barbara, Mairhofer, Juergen, Zanghellini, Jürgen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685491/ https://www.ncbi.nlm.nih.gov/pubmed/38017439 http://dx.doi.org/10.1186/s12934-023-02248-2

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