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Identification of copy neutral loss of heterozygosity on chromosomes 1p, 1q, and 6p among nonsyndromic cleft lip and/or without cleft palate with hypodontia

BACKGROUND: Nonsyndromic cleft lip and/or without cleft palate (NSCL/P) with or without hypodontia is a common developmental aberration in humans and animals. This study aimed to identify the loss of heterozygosity (LOH) involved in hypodontia and NSCL/P pathogenesis. METHODS: This is a cross-sectio...

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Detalles Bibliográficos
Autores principales: Ghazali, Norliana, Rahman, Normastura Abd, Kannan, Thirumulu Ponnuraj, Ahmad, Azlina, Sulong, Sarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685534/
https://www.ncbi.nlm.nih.gov/pubmed/38031027
http://dx.doi.org/10.1186/s12903-023-03464-3