SHED-derived exosomes attenuate trigeminal neuralgia after CCI of the infraorbital nerve in mice via the miR-24-3p/IL-1R1/p-p38 MAPK pathway

BACKGROUND: Microglial activation in the spinal trigeminal nucleus (STN) plays a crucial role in the development of trigeminal neuralgia (TN). The involvement of adenosine monophosphate-activated protein kinase (AMPK) and N-methyl-D-aspartate receptor 1 (NMDAR1, NR1) in TN has been established. Init...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Rong, Fang, Yuxin, Zhang, Yuyao, Liu, Liu, Li, Na, Wu, Jintao, Yan, Ming, Li, Zehan, Yu, Jinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685568/
https://www.ncbi.nlm.nih.gov/pubmed/38031158
http://dx.doi.org/10.1186/s12951-023-02221-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685568/
https://www.ncbi.nlm.nih.gov/pubmed/38031158
http://dx.doi.org/10.1186/s12951-023-02221-6

Ejemplares similares