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SHED-derived exosomes attenuate trigeminal neuralgia after CCI of the infraorbital nerve in mice via the miR-24-3p/IL-1R1/p-p38 MAPK pathway

BACKGROUND: Microglial activation in the spinal trigeminal nucleus (STN) plays a crucial role in the development of trigeminal neuralgia (TN). The involvement of adenosine monophosphate-activated protein kinase (AMPK) and N-methyl-D-aspartate receptor 1 (NMDAR1, NR1) in TN has been established. Init...

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Detalles Bibliográficos
Autores principales:	Guo, Rong, Fang, Yuxin, Zhang, Yuyao, Liu, Liu, Li, Na, Wu, Jintao, Yan, Ming, Li, Zehan, Yu, Jinhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685568/ https://www.ncbi.nlm.nih.gov/pubmed/38031158 http://dx.doi.org/10.1186/s12951-023-02221-6

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