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Microglial function, INPP5D/SHIP1 signaling, and NLRP3 inflammasome activation: implications for Alzheimer’s disease

Recent genetic studies on Alzheimer’s disease (AD) have brought microglia under the spotlight, as loci associated with AD risk are enriched in genes expressed in microglia. Several of these genes have been recognized for their central roles in microglial functions. Increasing evidence suggests that...

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Detalles Bibliográficos
Autores principales: Terzioglu, Gizem, Young-Pearse, Tracy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685641/
https://www.ncbi.nlm.nih.gov/pubmed/38017562
http://dx.doi.org/10.1186/s13024-023-00674-9