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TIGIT(+) NK cells in combination with specific gut microbiota features predict response to checkpoint inhibitor therapy in melanoma patients

BACKGROUND: Composition of the intestinal microbiota has been correlated to therapeutic efficacy of immune checkpoint inhibitors (ICI) in various cancer entities including melanoma. Prediction of the outcome of such therapy, however, is still unavailable. This prospective, non-interventional study w...

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Detalles Bibliográficos
Autores principales: Tsakmaklis, Anastasia, Farowski, Fedja, Zenner, Rafael, Lesker, Till Robin, Strowig, Till, Schlößer, Hans, Lehmann, Jonas, von Bergwelt-Baildon, Michael, Mauch, Cornelia, Schlaak, Max, Knuever, Jana, Schweinsberg, Viola, Heinzerling, Lucie M., Vehreschild, Maria J. G. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685659/
https://www.ncbi.nlm.nih.gov/pubmed/38017389
http://dx.doi.org/10.1186/s12885-023-11551-5