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TIGIT(+) NK cells in combination with specific gut microbiota features predict response to checkpoint inhibitor therapy in melanoma patients
BACKGROUND: Composition of the intestinal microbiota has been correlated to therapeutic efficacy of immune checkpoint inhibitors (ICI) in various cancer entities including melanoma. Prediction of the outcome of such therapy, however, is still unavailable. This prospective, non-interventional study w...
Autores principales: | Tsakmaklis, Anastasia, Farowski, Fedja, Zenner, Rafael, Lesker, Till Robin, Strowig, Till, Schlößer, Hans, Lehmann, Jonas, von Bergwelt-Baildon, Michael, Mauch, Cornelia, Schlaak, Max, Knuever, Jana, Schweinsberg, Viola, Heinzerling, Lucie M., Vehreschild, Maria J. G. T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685659/ https://www.ncbi.nlm.nih.gov/pubmed/38017389 http://dx.doi.org/10.1186/s12885-023-11551-5 |
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