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Knock-in mice expressing a humanized arachidonic acid 15-lipoxygenase (Alox15) carry a partly dysfunctional erythropoietic system
Arachidonic acid 15-lipoxygenases (ALOX15) play a role in mammalian erythropoiesis but they have also been implicated in inflammatory processes. Seven intact Alox genes have been detected in the mouse reference genome and the mouse Alox15 gene is structurally similar to the orthologous genes of othe...
Autores principales: | Reisch, Florian, Heydeck, Dagmar, Schäfer, Marjann, Rothe, Michael, Yang, Jiaxing, Stehling, Sabine, Püschel, Gerhard P., Kuhn, Hartmut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685687/ https://www.ncbi.nlm.nih.gov/pubmed/38030974 http://dx.doi.org/10.1186/s11658-023-00511-3 |
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