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Anti-epidermal growth factor receptor treatment for patients with NeoRAS wild-type metastatic colorectal cancer: a case report of two cases

The NeoRAS phenomenon is defined as the conversion of tumor RAS status from mutant-type (MT) to wild-type (WT) after systemic chemotherapy in metastatic colorectal cancer (mCRC). Cetuximab, an anti-epidermal growth factor receptor (EGFR) antibody, is effective in patients with RAS WT mCRC but ineffe...

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Detalles Bibliográficos
Autores principales: Harada, Kazuaki, Yuki, Satoshi, Kawamoto, Yasuyuki, Nakamura, Takeaki, Kaneko, Shiho, Ishida, Koichi, Sakamoto, Naoya, Komatsu, Yoshito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685759/
https://www.ncbi.nlm.nih.gov/pubmed/38033418
http://dx.doi.org/10.1177/17588359231216090