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Metabolic labelling of DNA in cells by means of the “photoclick” reaction triggered by visible light

Two pyrene-tetrazole conjugates were synthesized as photoreactive chromophores that allow for the first time the combination of metabolic labelling of DNA in cells and subsequent bioorthogonal “photoclick” modification triggered by visible light. Two strained alkenes and three alkene-modified nucleo...

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Detalles Bibliográficos
Autores principales: Rieger, Lisa, Pfeuffer, Bastian, Wagenknecht, Hans-Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685802/
https://www.ncbi.nlm.nih.gov/pubmed/38033731
http://dx.doi.org/10.1039/d3cb00150d