An enhanced biophysical screening strategy to investigate the affinity of ASOs for their target RNA

The recent and rapid increase in the discovery of new RNA therapeutics has created the perfect terrain to explore an increasing number of novel targets. In particular, antisense oligonucleotides (ASOs) have long held the promise of an accelerated and effective drug design compared to other RNA-based...

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Detalles Bibliográficos
Autores principales: Stulz, Rouven, Lerche, Michael, Luige, Olivia, Taylor, Agnes, Geschwindner, Stefan, Ghidini, Alice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685824/
https://www.ncbi.nlm.nih.gov/pubmed/38033730
http://dx.doi.org/10.1039/d3cb00072a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685824/
https://www.ncbi.nlm.nih.gov/pubmed/38033730
http://dx.doi.org/10.1039/d3cb00072a

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