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An enhanced biophysical screening strategy to investigate the affinity of ASOs for their target RNA
The recent and rapid increase in the discovery of new RNA therapeutics has created the perfect terrain to explore an increasing number of novel targets. In particular, antisense oligonucleotides (ASOs) have long held the promise of an accelerated and effective drug design compared to other RNA-based...
Autores principales: | Stulz, Rouven, Lerche, Michael, Luige, Olivia, Taylor, Agnes, Geschwindner, Stefan, Ghidini, Alice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685824/ https://www.ncbi.nlm.nih.gov/pubmed/38033730 http://dx.doi.org/10.1039/d3cb00072a |
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