Application and challenges of TCR and BCR sequencing to investigate T- and B-cell clonality in elastase-induced experimental murine abdominal aortic aneurysm

BACKGROUND: An abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease. Although its pathogenesis is still poorly understood, recent evidence suggests that AAA displays autoimmune disease characteristics. Particularly, T cells responding to AAA-related antigens in the aortic wal...

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Detalles Bibliográficos
Autores principales: Elster, Christin, Ommer-Bläsius, Miriam, Lang, Alexander, Vajen, Tanja, Pfeiler, Susanne, Feige, Milena, Yau Pang, Tin, Böttenberg, Marius, Verheyen, Sarah, Lê Quý, Khang, Chernigovskaya, Maria, Kelm, Malte, Winkels, Holger, Schmidt, Susanne V., Greiff, Victor, Gerdes, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686233/
https://www.ncbi.nlm.nih.gov/pubmed/38034381
http://dx.doi.org/10.3389/fcvm.2023.1221620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686233/
https://www.ncbi.nlm.nih.gov/pubmed/38034381
http://dx.doi.org/10.3389/fcvm.2023.1221620

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