Drug repositioning based on weighted local information augmented graph neural network

Drug repositioning, the strategy of redirecting existing drugs to new therapeutic purposes, is pivotal in accelerating drug discovery. While many studies have engaged in modeling complex drug–disease associations, they often overlook the relevance between different node embeddings. Consequently, we...

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Detalles Bibliográficos
Autores principales: Meng, Yajie, Wang, Yi, Xu, Junlin, Lu, Changcheng, Tang, Xianfang, Peng, Tao, Zhang, Bengong, Tian, Geng, Yang, Jialiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Problem Solving Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686358/
https://www.ncbi.nlm.nih.gov/pubmed/38019732
http://dx.doi.org/10.1093/bib/bbad431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686358/
https://www.ncbi.nlm.nih.gov/pubmed/38019732
http://dx.doi.org/10.1093/bib/bbad431

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