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Dynamics of T-cell Responses Following COVID-19 mRNA Vaccination and Breakthrough Infection in Older Adults

INTRODUCTION: While older adults generally mount weaker antibody responses to a primary COVID-19 vaccine series, T-cell responses remain less well characterized in this population. We compared SARS-CoV-2 spike-specific T-cell responses after 2- and 3-dose COVID-19 mRNA vaccination and subsequent bre...

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Detalles Bibliográficos
Autores principales: Datwani, Sneha, Kalikawe, Rebecca, Mwimanzi, Francis, Speckmaier, Sarah, Liang, Richard, Sang, Yurou, Waterworth, Rachel, Yaseen, Fatima, Lapointe, Hope R., Barad, Evan, DeMarco, Mari L., Holmes, Daniel T., Simons, Janet, Montaner, Julio S.G., Romney, Marc G., Brumme, Zabrina L., Brockman, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pathogens and Immunity 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686373/
https://www.ncbi.nlm.nih.gov/pubmed/38035132
http://dx.doi.org/10.20411/pai.v8i1.613