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Vaccination against the HDL receptor of S. japonicum inhibits egg embryonation and prevents fatal hepatic complication in rabbit model

BACKGROUND: Schistosomiasis is one of the most important neglected tropical infectious diseases to overcome and the primary cause of its pathogenesis is ectopic maturation of the parasite eggs. Uptake of cholesteryl ester from the host high-density lipoprotein (HDL) is a key in this process in Schis...

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Detalles Bibliográficos
Autores principales: Zhu, Jifeng, Zhang, Lina, Xue, Zechao, Li, Zilüe, Wang, Chun, Chen, Fanyan, Li, Yalin, Dai, Yang, Zhou, Yonghua, Zhou, Sha, Chen, Xiaojun, Okumura-Noji, Kuniko, Lu, Rui, Yokoyama, Shinji, Su, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686426/
https://www.ncbi.nlm.nih.gov/pubmed/38019787
http://dx.doi.org/10.1371/journal.pntd.0011749