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Vaccination against the HDL receptor of S. japonicum inhibits egg embryonation and prevents fatal hepatic complication in rabbit model
BACKGROUND: Schistosomiasis is one of the most important neglected tropical infectious diseases to overcome and the primary cause of its pathogenesis is ectopic maturation of the parasite eggs. Uptake of cholesteryl ester from the host high-density lipoprotein (HDL) is a key in this process in Schis...
Autores principales: | Zhu, Jifeng, Zhang, Lina, Xue, Zechao, Li, Zilüe, Wang, Chun, Chen, Fanyan, Li, Yalin, Dai, Yang, Zhou, Yonghua, Zhou, Sha, Chen, Xiaojun, Okumura-Noji, Kuniko, Lu, Rui, Yokoyama, Shinji, Su, Chuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686426/ https://www.ncbi.nlm.nih.gov/pubmed/38019787 http://dx.doi.org/10.1371/journal.pntd.0011749 |
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